泛昔洛韦, ≥99%
| 【编号】：129240 【产品名称】：泛昔洛韦, ≥99% 【规格】：50MG 【用途】：   泛昔洛韦, ≥99%
Product Name： Famciclovir
别名：2-[2-(2-氨基-9H-嘌呤-9-基)乙基]-1,3-丙二醇二乙酯
CAS号：104227-87-4
分子式：C14H19N5O4
分子量：321.33
介绍： Famciclovir
贮存： 储存温度-20°C
可溶性：
DMSO 64 mg/mL
Water 64 mg/mL
Ethanol 48 mg/mL
生化和生理学机理：
Description： IC50 Value： Refer to penciclovir Famciclovir is the diacetyl 6-deoxy analog of the active antiviral compound penciclovir with potential use in the treatment of infections caused by the herpes family of viruses [1]. Famciclovir, a synthetic acyclic guanine derivative, is a prodrug which, after oral administration, is rapidly metabolised to the highly bioavailable antiviral compound penciclovir [2]. in vitro： Famciclovir induced rapid, dose-dependent suppression of viral replication and reduction in alanine aminotransferase (ALT), with greatest efficacy in the 500-mg tid treatment group. HBV DNA reduction was maintained throughout the treatment period. ALT also steadily declined during the treatment period [3]. in vivo： In rat, following dosing at 40 mg/kg, famciclovir was rapidly and extensively metabolized to the active antiviral compound penciclovir, which reached peak concentrations in the plasma (mean 3.5 micrograms/ml) at 0.5 h [4]. Necrotic hepatitis
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