Sobetirome, ≥99%
| 【编号】：125416 【产品名称】：Sobetirome, ≥99% 【规格】：10MG 【用途】：   Sobetirome, ≥99%
Product Name： Sobetirome
CAS号：211110-63-3
分子式：C20H24O4
分子量：328.4
贮存： 储存温度-20°C
可溶性： DMSO
生化和生理学机理：
Sobetirome, also known as GC-1 and QRX-431, is a member of a class of compounds known as selective thyromimetics. Sobetirome is thyroid hormone beta-receptor agonist. Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through TRalpha activation in the heart. The tissue selective thyromimetic properties of sobetirome have been demonstrated in numerous animal models, which led to its clinical development as a novel cholesterol-lowering agent. Treatment of hypercholestemia obesity, and thyroid proliferative disorders.
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