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他米巴罗汀,≥99%
  【编号】:127943

  【产品名称】:他米巴罗汀,≥99%

  【规格】:1G

  【用途】:

  他米巴罗汀,≥99%

  Product Name: Tamibarotene
  别名:4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoicacid
  CAS号:94497-51-5
  分子式:C22H25NO3
  分子量:351.44
  介绍: Tamibarotene
  贮存: 储存温度-20°C
  可溶性:
  DMSO 70 mg/mL
  Water <1 mg/mL
  Ethanol 70 mg/mL
  生化和生理学机理:
  Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
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