YK-4-279
| 【编号】：127218 【产品名称】：YK-4-279 【规格】：10MG 【用途】：   YK-4-279
Product Name： YK-4-279
CAS号：1037184-44-3
分子式：C17H13Cl2NO4
分子量：366.2
贮存： 储存温度-20°C
可溶性： DMSO ≥100mg/mL
生化和生理学机理：
YK-4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. YK-4-279 inhibits Ewing's sarcoma family tumor (ESFT) cell growth; YK-4-279 induces apoptosis. ES-FLI1 is an oncogenic fusion protein found in Ewing’s sarcoma, a family of undifferentiated tumors that occur throughout the body. The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA.
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| 上一篇：XL-147, ≥98% | 下一篇：扎那米韦，≥99％ |
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